"The #1 Acne Treatment With Guaranteed Results" Acnezine - How It Works Acuzine's Natural Ingredients Help Protect the Skin, Reduce Swelling and Promote Healing of Scars. Most people who have reached or passed adolescence have suffered at least slightly from the unsightliness and irritation of acne. A few lucky people seem rarely or never to be touched by this problem. For the majority, acne is something that they have to deal with, perhaps mainly as teens, perhaps at least off and on throughout their lives. And for some people, acne is a terrible invader, always there, always irritating, always ugly, always on their minds, always interfering with their self-confidence and personal relationships. Acne is caused when the hair follicles in our skin get blocked. No one knows precisely why these blockages occur, nor why they are more severe in some people than in others, even in different members of the same family. It also is not known why acne commonly first occurs after puberty, although the sebaceous glands grow considerably at this time, which could be a factor. The oil produced by hair follicles, called sebum, is normally beneficial because it helps prevent the skin from drying and limits skin infections. But when sebum can't drain, it builds up and actually becomes a culture medium for bacteria. As pimples develop, the skin may become inflamed. This inflammation may last for a time even after a pimple bursts or heals (you shouldn't squeeze pimples, because squeezing can lead to more severe skin infections). In severe cases, scarring may take place, caused by imperfections in the inflammatory response to infection. It is not known why some people are more susceptible to acne scarring than others. Fortunately, most acne spots and inflammation heal over time, but the healing process can take months. Acuzine has natural ingredients that work to take care of the skin. They help control free radicals that cause skin damage, aging and wrinkling, and that can contribute to infection. Acuzine limits inflammation, helping take care of the ugly redness, and working to limit the inflammatory response that can cause scarring. And, Acuzine promotes healing. Active Ingredients: Vitamin E: Vitamin E is a fat-soluble vitamin that exists in eight different forms. Each form is active and useful in the body in its own way. Alpha Tocopheryl is the most active form of Vitamin E in humans, and is a powerful antioxidant. Antioxidants such as Vitamin E act to protect your cells against the effects of free radicals, which are potentially damaging byproducts of the body's metabolism and digestive system. Free radicals can cause cell damage that may contribute to the development of cardiovascular disease and cancer. Because skin is high in unsaturated fatty acids, which are especially susceptible to free radical damage, it can benefit from vitamin E protection. Vitamin E also can increase the effects of Vitamin C. Dimethylaminoethanol Bitartrate (DMAE): These are purchased only from reputable wholesalers. Each raw material in our products must come with a Certificate of Analysis obtained from the supplier. Our in house Quality Assurance team also analyzes the raw materials for authenticity. Alpha Lipoic Acid (as Thioctic Acid): Alpha Lipoic Acid (ALA), also known as Thioctic Acid, is a universal antioxidant. In other words, it is both fat and water soluble. As a result, ALA can travel more widely through the body than most antioxidants. ALA stops the activation of NF kappa B, so helping to suppress the inflammatory response within the cell. This can reduce the redness due to skin irritation. ALA has also been found to prevent and reverse scar formation. ALA controls a transcription factor called AP-1. AP-1 activates genes in the cell nucleus that produce collagen-digesting enzymes. The digestion of collagen promotes wrinkles, but ALA can work to inhibit this process. ALA helps recycle other antioxidants, such as Vitamin E and Vitamin C, making them more effective. ALA also helps the body produce energy and has been studied in connection with liver problems, radiation sickness, diabetes-related neuropathy, protection of DNA and even as an inhibitor of HIV. ALA is found in only small amounts in foods meaning that you can't get very much of it through diet alone. Ascorbyl Palmitate (as L-Ascorbic Acid): Your body needs Vitamin C (Ascorbic Acid) to form and maintain bones, blood vessels and skin. In particular, Ascorbic Acid helps form collagen. It also promotes the healing of cuts, abrasions and wounds to the skin, and helps regulate melanin production, contributing to reducing hyperpigmentation during outbreaks of acne. There are two forms of Ascorbic Acid, L-Ascorbic Acid and D-Ascorbic Acid. D-Ascorbic Acid is discarded by the body, meaning that L-Ascorbic Acid is the only useful form of Vitamin C. Ascorbyl Palmitate is a fat-soluble form of Ascorbic Acid. This quality may allow Ascorbyl Palmitate to act more effectively as an antioxidant than ordinary Ascorbic Acid within the lipid domains of your cells, protecting the membranes and low density lipoproteins (LPL) against oxidation. There are indications that Ascorbyl Palmitate similarly may be more efficient than ordinary Ascorbic Acid in recycling Vitamin E. Studies indicate that Ascorbic Acid helps protect the skin against light and helps prevent suppression of the immune system due to ultraviolet radiation. Ascorbic Acid is valuable in keeping teeth, bones, gums, cartilage, vertebra discs, joint linings, skin and blood vessels healthy. It is also been studied in relation to preventing infections and cancer, aiding the absorption of iron and reducing levels of lead in the blood. Because Ascorbic Acid is a water-soluble vitamin, it cannot be stored by the body except in very small amounts and must be replenished daily. Aloe Vera (Aloe vera) (leaf): Aloe Vera leaf contains enormous numbers of nutrients and beneficial compounds, including minerals, amino acids and vitamins. Aloe Vera is widely used in the treatment of wounds, minor burns and skin irritations, because it contains gibberlin and polysaccharides, which effectively decrease inflammation and promote wound healing. The lignins in Aloe Vera penetrate the skin and carry the healing effect into the tissues. Aloe Vera also helps to reduce scar tissue. It has been claimed that Aloe Vera leaf boosts the immune system. Collagen Hydrolyzed: About 25% of all body proteins consist of collagen. Hydrolyzed Collagen is simply collagen that has been broken down into smaller pieces by enzymes, which may ease the digestion and absorption of the amino acids in collagen by the intestine. Hydrolyzed Collagen is thought to help nourish the body's collagen-containing tissues, including cartilage, bones, tendons, ligaments and skin. Hydrolized Collagen also prevents moisture loss, and binds and retains water. Studies suggest that Hydrolyzed collagen may aid in the treatment of degenerative joint disease. Bioperine (Piper nigrum): Bioperine is a patented extract of black pepper and long pepper berries harvested in India. Black pepper is used in Ayurvedic medicine to treat fevers, digestive disorders, urinary difficulties, rheumatism, neuralgia and boils. Bioperine contains far more of the active content of black pepper than raw pepper does. The important point for Acuzine is that Bioperine increases the absorption of many supplements, including vitamins, minerals, amino acids and antioxidants, making the other active ingredients more active. Ubidecarenone Co-Enzyme Q10: Coenzyme Q10 is also known as ubidecarenone. It is made naturally in the body. A coenzyme is a substance needed for the proper functioning of an enzyme, a protein that speeds up the rate at which chemical reactions take place. Q10 refers to parts of the compound's chemical structure. Coenzyme Q10 is an antioxidant found in most body tissues. Like other antioxidants, it has been studied in relation to reducing aging of and damage to the skin. Tissue levels of coenzyme Q10 decrease as people get older. Coenzyme Q10 is used to produce the energy needed for cell growth and maintenance and has been examined in treament of HIV, cancer, and heart disease. References: Choi, S-W., Son, B-W., Son, Y-S., Park, Y-I., Lee, S-K. and Chung, M-H. The wound-healing effect of a glycoprotein fraction isolated from aloe vera. Br J Dermatol. 2001 145: 535-545. Kappus, H and Diplock, AT. Tolerance and safety of vitamin E: A toxicological position report. Free Radic Biol Med 1992; 13:55-74. Liu, J., Atamna, H., Kuratsune, H. and Ames, B.N. Delaying Brain Mitochondrial Decay and Aging with Mitochondrial Antioxidants and Metabolites. Ann NY Acad Sci 2002 959: 133-166. Packer, L., Weber, S.U. and Rimbach, G. Molecular Aspects of alpha-Tocotrienol Antioxidant Action and Cell Signalling J. Nutr. 2001131: 369-373.Perricone, N., Nagy, K., Horvath, F., Dajko, G., Uray, I. and Zs.-Nagy, I. The Hydroxyl Free Radical Reactions of Ascorbyl Palmitate as Measured in Various in Vitro Models. Biochem Biophys Res Comm. 1999 262: 661-665. Savini, I., Catani, M.V., Rossi, A., Duranti, G., Melino, G. and Avigliano, L. Characterization of Keratinocyte Differentiation Induced by Ascorbic Acid: Protein Kinase C Involvement and Vitamin C Homeostasis, J Invest Dermatol. 2002 118: 372-379.

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