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    Patients have increased hospitalization rate after gastric bypass surgery

 
    Patients who have gastric bypass surgery have double the rate of hospitalization in
    the year following the operation than in the year preceding surgery, according to a study in
    the October 19 issue of JAMA.

    Bariatric surgical procedures are an increasingly common treatment for morbid obesity,
    according to background information in the article. More than 100,000 Roux-en-Y
    gastric bypasses (RYGB)--the primary bariatric procedure now done--are performed
    annually in the United States. A recent systematic review and meta-analysis of bariatric
    procedures determined that the average percentage of excess weight loss after
    operation was 61 percent, with rates of resolution or improvement for the following
    co-existing illnesses: diabetes 86 percent, hyperlipidemia 70 percent, hypertension
    79 percent, and obstructive sleep apnea 84 percent. Utilization of inpatient services
    after RYGB is not well understood.

    David S. Zingmond, M.D., Ph.D., of the University of California, Los Angeles, and
    colleagues assessed the impact of RYGB on use of inpatient care by examining
    rates of inpatient hospitalization before and after RYGB performed in California
    between 1995 and 2004.

    In California from 1995-2004, a total of 60,077 California residents underwent RYGB
    for obesity, with 11,659 in 2004. The average age was 42.2 years, 84 percent of
    patients were women, and 88 percent were privately insured or self-pay. Average
    length of stay was 3.5 days. For patients with a year of follow-up (1995-2003), 19.3
    percent were readmitted within the first year after RYGB surgery compared with 7.9
    percent being admitted in the year before surgery. In a subset analysis of all patients
    (24,678) who underwent RYGB with complete 3-year follow-up, the average percentage
    of patients admitted in the year prior to RYGB was 8.4 percent. In each of the 3 years
    following RYGB, the rates of hospitalization remained increased, with 20.2 percent of
    patients readmitted in the first year after RYGB, 18.4 percent in the second year after,
    and 14.9 percent in the third year after. The cumulative admission rate for the 3-year
    period prior to RYGB was 20.2 percent compared with the cumulative 3-year admission
    rate after RYGB of 40.4 percent.

    For persons with 3 years of follow-up, average hospital charges were $33,672 for
    RYGB, $4,970 for hospitalizations in the 3 years before RYGB, and $20,651 for
    hospitalizations in the 3 years after RYGB. In the subset of patients with full 5 years
    of follow-up (1995-1999), postoperative admission rates remained elevated
    (average 13.3 percent) in the fifth year after operation.

    The most common reasons for admission prior to RYGB were obesity related problems
    (e.g., osteoarthritis, lower extremity cellulitis), and elective operation (e.g., hysterectomy),
    while the most common reasons for admission after RYGB were complications often
    thought to be procedure related, such as ventral hernia repair and gastric revision.

    "A working hypothesis in our study was that use of health care services should likewise
    improve, namely that inpatient care should decrease after RYGB. However, we found
    significant and sustained increases in the rates of hospital admission for morbidly obese
    patients after RYGB. Annual rates of hospital admission after RYGB are double than prior
    to operation and are sustained beyond a year in this population-based study," the
    authors write.

    "Our findings may have implications for payers and purchasers of health care. Rather
    than expecting a decrease in inpatient health care utilization after RYGB, the costs
    associated with inpatient hospitalization may remain elevated for as many as 5 years
    following RYGB. Analysis of 3-year charges before and after RYGB suggest that costs
    of post-RYGB-related procedures and complications may be 40 percent to 60 percent
    of the costs of RYGB itself."

    "The potential of RYGB for yielding long-term weight reduction and alleviation of
    obesity-related comorbid illnesses has significantly increased the rates of RYGB
    over the past decade. Despite these potential benefits, the current study demonstrates
    that the rates of hospitalization doubles in the years after operation and that many of
    these admissions are directly attributable to this procedure," the researchers conclude.

    (JAMA.2005; 294:1918-1924)

    Editor's Note: Dr. Zingmond is funded by a Mentored Clinical Scientist Award from the
    National Institute on Aging. Co-author Dr. McGory is funded by the Robert Wood
    Johnson Clinical Scholars Program at the University of California Los Angeles.

    Rachel Champeau
    JAMA and Archives Journals
    http://www.jamamedia.org


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